Year 4 Pilots

Using AI to Repurpose Small Molecules to Target Amyloid-tau Interactions in AD

Jeremy Linsley, Operant BioPharma This project will use a proprietary robotics and artificial intelligence to identify targets and clinically-tested drugs that could be repurposed for Alzheimer's disease by blocking the harmful interaction between Tau and Amyloid Precursor proteins.

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AI-assisted Prediction of Healthy Aging and Alzheimer’s Disease Progression

Chaitanya Gupta, ProbiusDX Inc., Steven Arnold, Massachusetts General Hospital. This project will use Probius QES, a novel technology that measure molecular vibrations in blood plasma samples, to identify and differentiate healthy aging vs Alzheimer’s Disease progression in a well characterized cohort of 1000+ individuals from MassGen.

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