Pilot Outcomes

Publication: Validation of commercial sleep-tracking wearables and nearables in healthy young and older adults

Authors: M.E. Searles, A. Licata, M. Cucinotta, K. Kainec, and R.M.C. Spencer Abstract Study objectives: Changes in sleep with aging are associated with risk for Alzheimer’s and other neurological diseases, risk of accidents, and can be a predictor of health decline. For this reason, continuous sleep monitoring is of great interest for researchers, clinicians, and family members. The objective of this study was to assess the validity of consumer sleep-tracking devices in older relative to young adults. Methods: Analyses were based on one night of sleep assessed in young (19-24 years; n=13) and older adults (56-80 years; n=19). Participants wore sleep-tracking wearables (Fitbit Sense 2, Oura Ring) and nearables (Withings Sleep Mat, Sleep Score Max) were positioned nearby. Sleep measures were compared to polysomnography. Results: Results suggest that devices may be less accurate in older…

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Publication: Replicable Bandits for Digital Health Interventions

Authors: Kelly W Zhang, Nowell Closser, Anna L Trella, Susan A Murphy Abstract Adaptive treatment assignment algorithms, such as bandit algorithms, are increasingly used in digital health intervention clinical trials. Frequently the data collected from these trials is used to conduct causal inference and related data analyses to decide how to refine the intervention, and whether to roll-out the intervention more broadly. This work studies inference for estimands that depend on the adaptive algorithm itself; a simple example is the mean reward under the adaptive algorithm. Specifically, we investigate the replicability of statistical analyses concerning such estimands when using data from trials deploying adaptive treatment assignment algorithms. We demonstrate that many standard statistical estimators can be inconsistent and fail to be replicable across repetitions of the clinical trial, even as the sample size grows large.…

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Publication: Kinematic correlates of early speech motor changes in cognitively intact APOE-ε4 carriers: a preliminary study using a color-word interference task

Authors: Mehrdad Dadgostar, Lindsay C Hanford, Jordan R Green, Brian D Richburg, Averi Taylor Cannon, Nelson V Barnett, David H Salat, Steven E Arnold, Marziye Eshghi Abstract Introduction: Alzheimer's disease (AD) is the most prevalent form of dementia and a major public health challenge. In the absence of a cure, accurate and innovative early diagnostic methods are essential for proactive life and healthcare planning. Speech metrics have shown promising potential for identifying individuals with mild cognitive impairment (MCI) and AD, prompting investigation into whether speech motor features can detect elevated risk even prior to cognitive decline. This preliminary study examined whether speech kinematic features measured during a color-word interference task could distinguish cognitively normal APOE-ε4 carriers (ε4+) from non-carriers (ε4-). Methods: Sixteen cognitively normal older adults (n = 9 ε4+, n = 7 ε4-) completed…

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Grant Funding: University of Buffalo Center for Advanced Technology in Big Data and Health Sciences (UB CAT)

  • Post category:A33 - Auspex

Auspex Medix received $40,000 in matching funds from UB CAT Source: https://www.buffalo.edu/partnerships/about/news-events/news-detail-template.host.html/content/shared/www/partnerships/news/2025/New-hearing-loss-test-checks-the-eyes-not-the-ears.detail.html

Continue ReadingGrant Funding: University of Buffalo Center for Advanced Technology in Big Data and Health Sciences (UB CAT)

New Product Launch: Lumia 2 Smart Earrings

  • Post category:A30 - Lumia

Lumia is bringing their lightest wearable tech for measuring blood-flow to a whole new market with the introduction of a fine jewelry inspired smart-earring form factor with expanded health monitoring features. BOSTON – Nov. 18, 2025 – Lumia today announced the launch of Lumia 2, the world’s first smart earrings that continuously track real-time blood flow to your head, giving anyone instant insight into how blood flow affects energy, focus, and mental clarity. Originally developed with Johns Hopkins, Duke, and Harvard researchers to help patients with chronic blood flow disorders like POTS (Postural Orthostatic Tachycardia Syndrome) and Long COVID-19, Lumia is now available to everyone for the first time.Indistinguishable from fine jewelry, Lumia 2 can be worn as huggie hoops, cuffs, and studs offered in gold, silver, and clear finishes, and also attaches to any…

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