Past Webinar – Technology Use in Alzheimer’s Disease Research: Current Status & Future Promise, Rhoda Au

https://youtu.be/sXAMmZZ5YEM?si=d5QDssWNCXVmchEP Abstract: Digital technologies offer unprecedented opportunities to revolutionize cognitive health monitoring and Alzheimer’s disease prevention. Current high-burden, clinic-based assessments can be augmented by passive engagement technologies—leveraging smartphones and their array of embedded sensors for continuous, unobtrusive data collection. At the Framingham Heart Study and BU Alzheimer’s Disease Research Center, multi-sensor approaches combining smartphone applications, digital voice, eye-tracking, and in-home monitoring are being deployed to detect subtle cognitive and behavioral changes. Through the Davos Alzheimer’s Collaborative, a global minimal viable protocol has been launched, integrating digital and blood-based biomarkers across diverse populations. Data sharing via the Alzheimer’s Disease Data Initiative (ADDI) is accelerating discovery through open challenges and collaborative analytics. This paradigm shift emphasizes inclusivity, rethinking traditional study designs, and advancing from digital phenotyping to truly dynamic, multi-dimensional digital biomarkers. The long-term goal is early…

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Past Webinar – Sleep Measurement: Challenges and Opportunities to Measure Sleep Health, Rebecca Spencer

https://youtu.be/wmz-rMzTMDU?si=B-t8xSVptTgDL78p Abstract: Sleep plays a vital role in cognitive function, emotional regulation, and overall health, effects that are particularly salient in older adults and individuals living with Alzheimer’s disease and related dementias (ADRD). In this webinar, Dr. Rebecca Spencer, a leading sleep researcher and Professor at UMass Amherst, provides a comprehensive overview of sleep’s physiological functions, such as memory consolidation and glymphatic waste clearance, and how these processes are altered by aging and neurodegenerative disease. Dr. Spencer examines the evolution of sleep measurement technologies, from gold-standard polysomnography to consumer-grade wearables and actigraphy. She critically assesses the validity and limitations of these tools, particularly when applied to aging and ADRD populations, and highlights challenges such as device comfort, physiological variability, and the need for population-specific validation. Finally, she explores promising avenues for technological innovation and targeted…

Continue ReadingPast Webinar – Sleep Measurement: Challenges and Opportunities to Measure Sleep Health, Rebecca Spencer