Pilots

Publication: Developing an Equitable Machine Learning-Based Music Intervention for Older Adults At Risk for Alzheimer Disease: Protocol for Algorithm Development and Validation

Authors: Chelsea S Brown, Luna Dziewietin, Virginia Partridge, Jennifer Rae Myers Abstract Background: Given the high prevalence and cost of Alzheimer disease (AD), it is crucial to develop equitable interventions to address lifestyle factors associated with AD incidence (eg, depression). While lifestyle interventions show promise for reducing cognitive decline, culturally sensitive interventions are needed to ensure acceptability and engagement. Given the increased risk for AD and health care barriers among rural-residing older adults, tailoring interventions to align with rural culture and distinct needs is important to improve accessibility and adherence. Objective: This protocol aims to develop an intelligent recommendation system capable of identifying the optimal therapeutic music components to elicit engagement and resonate with diverse rural-residing older adults at risk for AD. Aim 1 is to develop culturally inclusive user personas for rural-residing older adults to understand…

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Publication: Passive Measures of Physical Activity and Cadence as Early Indicators of Cognitive Impairment: Observational Study

Authors: Huitong Ding, Stefaniya Brown, David R Paquette, Taylor A Orwig, Nicole Spartano, Honghuang Lin Abstract Background: Emerging research shows regular physical activity reduces cognitive decline risk, but most studies rely on self-reported measures, which are limited by recall bias, subjectivity, and a lack of continuous monitoring capability. Objective: This study aimed to explore passive physical activity measures as early indicators of cognitive impairment by examining their association with cognitive impairment incidence and neuropsychological (NP) test performance. Methods: We included participants from the Framingham Heart Study (FHS), a community-based cohort with longitudinal cognitive impairment surveillance. Participants wore an Actical accelerometer for at least 3 days, excluding bathing. Thirty physical activity measures were grouped into intensity-specific durations, step and cadence summaries, and peak cadence. Cox proportional hazard models were applied to assess their associations with incident…

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Oral Presentation: Alzheimer’s Association International Conference 2025 – Technology And Dementia Preconference

Jennifer Flexman presented "Improving Access to Dementia Care though AI-Powered Cognitive Rehabilitation Therapy" at the Technology And Dementia Preconference during Session 5: Data Blitz.

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Award: Jiani Zeng, co-founder and CPO of Butlr wins 2025 McKnight’s Women of Distinction award in the Commercial Excellence category

The technology designed by Zeng has been key in improving senior living and care operations, helping staff members effectively monitor residents through motion detection, enabling them to respond quickly to acute health risks without compromising resident privacy.Forster Stubbs, McKnight Senior Living The work of Jiani Zeng, a Chinese designer, researcher, and co-founder and chief product officer of Butlr Technologies, often takes place in the background, but the results always end up at the forefront. Thanks in part to her efforts, Butlr is the first company to fuse artificial intelligence and body heat sensing technology to provide insights into how humans use indoor space for living and working while ensuring anonymity. This technology has significant applications in the senior living and care sector and helped earn Zeng a 2025 McKnight’s Women of Distinction award in the Commercial Excellence…

Continue ReadingAward: Jiani Zeng, co-founder and CPO of Butlr wins 2025 McKnight’s Women of Distinction award in the Commercial Excellence category

Patent Awarded: AI powered mobility assessment system (No. US 12,343,138 B2)

Abstract: To assess the mobility of a user, a mobility assessment system obtains a video of a user having a plurality of video frames from a camera. The mobility assessment system generates a three-dimensional (3D) skeleton model of the user based on the plurality of video frames, and determines a range of motion of the user based on a change in position of the 3D skeleton model over the plurality of video frames. Then the mobility assessment system provides an indication of the range of motion of the user for display. Also, the mobility assessment system delivers tailored exercises and suggestions to enhance user mobility and reduce the risk of falls. Source: US-12343138-B2

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