Abstract
This poster presents novel functional aging biomarkers and bioelectronic treatments that have been successfully combined to activate neuroplastic restoration of multiple domains of intrinsic capacity in older adults. A new class of digital biomarkers using a head-mounted “phybrata” wearable sensor is used to quantify impairments to multiple physiological systems that contribute to degraded intrinsic capacity. Phybrata biomarkers have enabled development of a non-invasive bioelectronic vestibular stimulation device and 6-week treatment protocol that have been shown to deliver large and persistent neuroplastic restoration of sensory, locomotor, cognitive, and psychological domains of intrinsic capacity in study populations from 50-95 years of age.
