Investigators:
Wenyao Xu, Auspex Medix
Wei Sun, University at Buffalo
MassAITC Cohort: Year 5 (AD/ADRD)

Initial Proposal Abstract: Hearing loss affects nearly half of adults over the age of 75 and is closely linked to memory loss and dementia. Many older adults never receive a proper hearing test because current methods require active listening and clear responses, which can be difficult for people with memory or attention problems. As a result, hearing loss often goes undetected until it begins to seriously affect daily life.
AudioSight, developed by Auspex Medix and University at Buffalo, is a new, easy-to-use smartphone tool that helps detect hearing loss using a small camera attachment and artificial intelligence (AI). Instead of asking users to respond to sounds, AudioSight measures tiny, natural changes in the eyes – called the Auditory Pupillary Response (APR) – that happen automatically when a person hears a sound. This allows hearing to be tested passively and comfortably at home or in a clinic without needing any special equipment or training.
In this pilot study, the research team will test AudioSight with older adults, including those with early memory changes or dementia. The study will collect eye response data during sound tests, compare results to standard hearing exams, and gather feedback from users and caregivers about how easy the system is to use. The goal is to make hearing screening simpler, faster, and more accessible for everyone, helping doctors and families catch hearing problems early and improve quality of life for older adults.
Outcomes:
- Grant Funding: NIH R01: mHealth Technologies for Assessing Hearing Disorders
Project Abstract Sound Sensitivity and Tolerance (SST) disorders represent an urgent public health challenge in hearing disorders, affecting over 350,000 new patients annually in the United States with an economic burden exceeding $14 billion. While SST frequently co-occurs with conditions like autism spectrum disorder, PTSD, and migraine, current clinical assessment… Read more: Grant Funding: NIH R01: mHealth Technologies for Assessing Hearing Disorders - Poster Presentation: a2 National Symposium 2026
Title: AudioSight AI-Powered At-Home Hearing Screening for Older Adults Authors: Chuhui Liu, Wei Sun, Wenyao Xu - Grant Funding: University of Buffalo Center for Advanced Technology in Big Data and Health Sciences (UB CAT)
Auspex Medix received $40,000 in matching funds from UB CAT Source: https://www.buffalo.edu/partnerships/about/news-events/news-detail-template.host.html/content/shared/www/partnerships/news/2025/New-hearing-loss-test-checks-the-eyes-not-the-ears.detail.html
